123IV.
Platforms Diagnostics Oncology Infusion Team Patents Contact
123IV — AI-ENABLED MEDTECH

AI-Enabled MedTech Without the Traditional Workflow

  • Diagnose without a specimen.
  • Detect and treat cancer at the surgical margin.
  • Automatically correct IV infusion interruptions.

Three patented technology platforms designed to eliminate delays, unnecessary steps, and preventable clinical workflow failures.

Working Prototype
123-CY diagnostic device prototype, a fingertip-scanning cylinder unit, shown with a finger resting on the scan surface
FIG. 1 — Working prototype, unit 123-CY. The optical acquisition module shown here is real hardware, not a concept render.
PLATFORM 01 — DIAGNOSTICS

Diagnosis, at the speed of light

A laser, a sensor, and a trained model replace the swab, the vial, and the wait.

NO-SPECIMEN · FINGERTIP SPECTROSCOPY + AI
Patient
Fingertip presented
Illuminate
Low-power laser scan
Spectral Signature
Molecular-level read
ML Classification
Trained on clinical data
Result
Under 30 seconds
FIG. 2 — Signal path from optical acquisition through spectral processing and classification to reported result. No specimen is drawn, transported, or processed at any stage.
455
patients enrolled in the clinical validation study
0.896
AUROC achieved for infection detection
3
care settings validated — ER, ICU, urgent care
<30s
from scan to result, with no lab in the loop
Read the peer-reviewed manuscript on MDPI →
PLATFORM 02 — SURGICAL ONCOLOGY

Detect. Treat. Confirm.

The next generation of the optical platform, built for the operating room instead of the bedside.

RAMAN + ELASTOGRAPHY + FOCAL TREATMENT · PIPELINE
Detect
Raman + elastography margin scan
Treat
Focal treatment at the margin
Confirm
Re-scan before closing
FIG. 3 — Intraoperative cycle: margin detection, focal treatment, and confirmatory re-scan performed with a single probe, in place, without a separate pathology loop.

Built on the same optical and machine-learning foundation as the point-of-care diagnostic platform, extended for the precision a surgical margin demands. Raman spectroscopy identifies suspect tissue; elastography adds mechanical context; focal treatment and a confirmatory re-scan close the loop before the surgeon closes the incision.

Pat. 12,702,304
"Intraoperative Probe for Cancer Diagnosis and Treatment," issued Aug 11, 2026.
Handheld probe delivering focal treatment during surgery, alongside a robotic-arm delivery concept for the same probe
Handheld delivery today; robotic-assisted delivery in development.
PLATFORM 03 — INFUSION

Correct the problem before the alarm becomes the problem

Most IV pump alarms aren't emergencies — they're kinked tubing and upstream occlusions that can be corrected before anyone needs to respond.

CLOSED-LOOP IV ALARM MITIGATION · WITH STEVENS INSTITUTE
Sense
Detect
Correct
Confirm
FIG. 4 — Closed-loop correction: line sensing, failure detection, mechanical correction, and confirmation, repeating continuously — a retrofit module, not a pump replacement.

Alarm fatigue has been recognized as one of the most significant health-technology safety hazards for over a decade, and clinical alarm safety has been a mandated National Patient Safety Goal since 2014.

85–99%
of clinical alarms are false, non-actionable, or clinically insignificant, per The Joint Commission's Sentinel Event Alert.

Built with Team A9 at the Stevens Institute of Technology, this retrofit module mechanically detects and corrects tubing failures before they escalate to an alarm — designed to work around the pump infrastructure hospitals already own.

Version 1 prototype of the autonomous IV correction arm, mounted on an IV pole and reaching toward the tubing
Version 1 prototype — the retrofit arm, built and mounted on a standard IV pole.
Stevens Innovation Expo
Watch the coverage
Team A9's first-generation prototype, unveiled with 123IV →
THE TEAM

Surgeons and engineers

A small team spanning clinical medicine, optical engineering, and machine learning — built around one surgeon's decade of patented device work.

AC

Allen B. Chefitz, MD

Founder & CEO — Surgeon / Scientist

Led the design, build, and clinical validation of the no-specimen diagnostic device. Holds multiple patents across the diagnostic and therapeutic space.

EL

Elisa Long, MD

Chief Operating Officer

MS in Computer Science, MIT. Leads partnership development and study execution, including collaborations with Northeastern University and MIT CSAIL.

RS

Rohit Singh, PhD

Scientific Advisor

Research scientist at MIT specializing in machine learning and genomics. Co-inventor of the no-specimen diagnostic device and co-founder of Martini.ai.

YY

Yongwu Yang, PhD

Consultant — Optical Engineering

PhD in Physical Chemistry, MIT. Brought Raman spectroscopy expertise to the finger-inserted diagnostic device.

GV

Gregg Vesonder, PhD

Advisor — Systems Engineering

Former Bell Labs engineer, now on the faculty at Stevens Institute of Technology. Advises on system architecture and scalable deployment.

PS

Peter Szolovits, PhD

Scientific Advisor

Professor at MIT EECS and head of the Clinical Decision-Making Group at MIT CSAIL, with an appointment in the Harvard/MIT HST program.

INTELLECTUAL PROPERTY

A portfolio of protected inventions

Eight issued U.S. patents so far, organized by platform, plus continuations, foreign filings, and pending applications.

No-Specimen Diagnostics
11,452,454
Self Administered Non-Invasive Transcutaneous Viral Detector
Sep 27, 2022
11,304,605
Self Administered Non-Invasive Transcutaneous Viral Detector
Apr 19, 2022
12,121,321
Self Administered Non-Invasive Transcutaneous Viral Detector
Oct 22, 2024
11,291,408
Eyewear System for Detecting and Indicating Presence of Coronavirus
Apr 5, 2022
Precision Surgical Oncology
12,702,304
Intraoperative Probe for Cancer Diagnosis and Treatment
Aug 11, 2026
Autonomous Infusion
11,872,708
Monitoring and Maintaining an Intravenous Assembly Without Medical Staff Involvement for Safe Distancing Enforcement
Jan 16, 2024
10,906,180
Monitoring and Maintaining an Intravenous Assembly Without Medical Staff Involvement for Safe Distancing Enforcement
Feb 2, 2021
12,121,765
System for Monitoring and Maintaining an Intravascular Assembly
Oct 22, 2024

Along with several continuation patents, foreign applications, and pending filings.

Have a pilot site, a partnership, or a press question?

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